Will I develop tolerance to your prescribed medication? - Cannadoc
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Interestingly, patients tend to quickly develop tolerance to side effects of our prescribed medication (over a few days), but not to its beneficial effects. So over time, escalation in dose is not generally needed, and often patients can maintain a stable daily dose for many years.

Reference: MacCallum CA and Russo EB. Practical considerations in medical cannabis administration and dosing. European Journal of Internal Medicine 2018; 49, 12-19.

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